ZSA-51

• Description :

  ZSA-51 is a potent and orally active STING agonist. ZSA-51 shows anticancer activity. ZSA-51 remodeles immune microenvironment both in tumor and lymph node[1].

• UNSPSC :

  12352005

• Target :

  STING

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  97.27

• Solubility :

  DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  COC(CCN1C(C2=C(C3=CC(OC)=C(C=C3S2)OC)C1=O)=O)=O

• Molecular Formula :

  C16H15NO6S

• Molecular Weight :

  349.36

• References & Citations :

  [1]Zhao HY, et al. An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment. Cell Chem Biol. 2025 Jan 24:S2451-9456 (25) 00004-2.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3084542-49-1]