Antibacterial agent 261

CAT: 0804-HY-168853Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-168853Size:1 Each
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Description
Antibacterial agent 261 (compound 43) is a potent inhibitor of peptidomimetic peptide deformylase (PDF), with IC50 of 2.5 and 10.6 nM for S. aureus and E. coli, respectively[1].
CAS Number
[3036109-97-1]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C([C@H](CCCC)CN(C=O)O)N1CCC[C@H]1C2=NN=C(C3=CC=CS3)S2
Molecular Formula
C18H24N4O3S2
Molecular Weight
408.54
References & Citations
[1]Shouning Yang, et al. Design, Synthesis, and Biological Evaluation of 1,3,4-Thiadiazole Derivatives as Novel Potent Peptide Deformylase Inhibitors for Combating Drug-Resistant Gram-Positive and -Negative Bacteria. J Med Chem. 2025 Jan 7. doi: 10.1021/acs.jmedchem.4c02177
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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