5S (6R) -EET

• Description:

  5S (6R) -EET is the metabolite of Arachidonic acid (HY-109590) . 5S (6R) -EET activates the synthesis of endogenous prostaglandin (PGE2), which inhibits the Na+ absorption, increases the intracellular Ca2+, and promotes the depolarization of transmembrane voltage. 5S (6R) -EET is more active than 5R (6S) -EET (HY-168382) [1].

• UNSPSC:

  12352211

• Target:

  Endogenous Metabolite; Prostaglandin Receptor

• Related Pathways:

  GPCR/G Protein; Metabolic Enzyme/Protease

• Field of Research:

  Others

• Smiles:

  OC (CCC[C@H]1[C@H] (O1) C/C=C\C/C=C\C/C=C\CCCCC) =O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.47

• References & Citations:

  [1]Sakairi Y, et al., 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis. Am J Physiol. 1995 May;268 (5 Pt 2) :F931-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  98103-47-0