(5S,6R)-DiHETE

• UNSPSC Description:

  (5S,6R)-DiHETE is an enantiomer of (5,6)-DiHETEs. (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC50 of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/5s-6r-dihete.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(O)=O

• Molecular Weight:

  336.47

• References & Citations:

  [1]Muller A, Rechencq E, Kugel C, et al. Comparative biological activities of the four synthetic (5, 6)-dihete isomers[J]. Prostaglandins, 1989, 38(6): 635-644.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  82948-88-7