AGN-190383

• Description:

  AGN-190383 is a bee venom phospholipase A2 inhibitor. AGN 190383 inhibits both hormone-operated and depolarization-dependent calcium mobilization as well as fMLP stimulated increases in free cytosolic calcium. AGN-190383 has anti-inflammatory activity[1].

• UNSPSC:

  12352005

• Target:

  Phospholipase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C1OC(C(C(CCCCCCCCCCCC)OC(C)=O)=C1)O

• Molecular Formula:

  C19H32O5

• Molecular Weight:

  340.45

• References & Citations:

  [1]De Vries GW, et al. AGN 190383, a novel phospholipase inhibitor with topical anti-inflammatory activity. Agents Actions. 1991 Sep;34 (1-2) :70-2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Phospholipase A

• CAS Number:

  [120755-15-9]