Products for Research Use Only
RegisterLogin

Lodoxamide (tromethamine) (Standard)

CAT: 0804-HY-16289R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-16289R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lodoxamide (tromethamine) (Standard) is the analytical standard of Lodoxamide (tromethamine) . This product is intended for research and analytical applications. Lodoxamide tromethamine (U-42585E) is a medication for the treatment of prophylaxis of mast cell-mediated allergic disease.
CAS Number
63610-09-3
UNSPSC
12352100
Target
Histamine Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Endocrinology
Smiles
N#CC1=CC(NC(C(O)=O)=O)=C(Cl)C(NC(C(O)=O)=O)=C1.OCC(CO)(N)CO.OCC(CO)(N)CO
Molecular Formula
C19H28ClN5O12
Molecular Weight
553.91
References & Citations
[1]Watt GD, et al. Protective effect opf lodoxamide tromethamine on allergen inhalation challenge. J Allergy Clin Immunol. 1980 Oct;66 (4) :286-94.|[2]Barr ML, et al. Addition of a mast cell stabilizing compound to organ preservation solutions decreases lung reperfusion injury. J Thorac Cardiovasc Surg. 1998 Mar;115 (3) :631-6; discussion 636-7.|[3]Mann JS, et al. Inhaled lodoxamide tromethamine in the treatment of perennial asthma: a double-blind placebo-controlled study. J Allergy Clin Immunol. 1985 Jul;76 (1) :83-90.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Lodoxamide Tromethamine

Lodoxamide Tromethamine is the tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity. Upon administration to the eye, lodoxamide tromethamide inhibits type I immediate hypersensitivity reaction by preventing the antigen-stimulated calcium influx into mast cells, thereby inhibiting release of histamine. Lodoxamide tromethamide also prevents the release of slow-reacting substances of anaphylaxis (SRS-A) and inhibits eosinophil chemotaxis.

CAS Number63610-09-3
PubChem CID11192129
IUPAC Namebis(2-amino-2-(hydroxymethyl)propane-1,3-diol);2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid
Molecular FormulaC19H28ClN5O12
Molecular Weight553.9
Topological Polar Surface Area330
Hydrogen Bond Donor Count12
Hydrogen Bond Acceptor Count15
Rotatable Bond Count10
Heavy Atom Count37
Formal Charge0
Complexity543
SMILES
C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N.C(C(CO)(CO)N)O.C(C(CO)(CO)N)O
InChI
InChI=1S/C11H6ClN3O6.2C4H11NO3/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21;2*5-4(1-6,2-7)3-8/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21);2*6-8H,1-3,5H2
InChIKey
JJOFNSLZHKIJEV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Lodoxamide Tromethamine
CAS: 63610-09-3
CID: 11192129
Formula: C19H28ClN5O12
MW: 553.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight553.9
Hydrogen Bond Donor Count12
Hydrogen Bond Acceptor Count15
Rotatable Bond Count10
Exact Mass553.1422990
Monoisotopic Mass553.1422990
Topological Polar Surface Area330 Ų
Heavy Atom Count37
Formal Charge0
Complexity543
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-16289-01Lodoxamide (tromethamine)
HY-14270R-01Lodoxamide (Standard)
HY-A0195RCarboprost (tromethamine) (Standard)
HY-B0138R-01Ketorolac (tromethamine salt) (Standard)
HY-12956ARDinoprost (tromethamine salt) (Standard)
HY-14270-01Lodoxamide
HY-167706-01Diethyl-Lodoxamide
HY-114577Palifosfamide (tromethamine)
HY-109083ACilofexor (tromethamine)
HY-A0195-01Carboprost (tromethamine)

Alternative Products

CatalogName
MBS3615357-01Lodoxamide tromethamine
A17969-5Lodoxamide Tromethamine 5mg
A17969-200Lodoxamide Tromethamine 200mg
A17969-50Lodoxamide Tromethamine 50mg
A17969-100Lodoxamide Tromethamine 100mg
A17969-25Lodoxamide Tromethamine 25mg
A17969-10Lodoxamide Tromethamine 10mg
A17969-10mM-DLodoxamide Tromethamine 10mM * 1mL in DMSO
MBS3608754-01Lodoxamide

Popular Products