PTX-BD10-2

• Description :

  PTX-BD10-2 (BD10-2) is an orally active TrkB/C modulator. PTX-BD10-2 ameliorates BFCN degeneration. PTX-BD10-2 restores cholinergic neurite integrity, alleviates cholinergic neurite atrophy. PTX-BD10-2 can be used in the research of Alzheimer's disease[1].

• Product Name Alternative :

  BD10-2

• UNSPSC :

  12352005

• Target :

  Trk Receptor

• Related Pathways :

  Neuronal Signaling; Protein Tyrosine Kinase/RTK

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Smiles :

  COCCN(CCOC)C1=CC=C(C(C)C2=CC=C(N(CCOC)CCOC)C=C2)C=C1

• Molecular Formula :

  C26H40N2O4

• Molecular Weight :

  444.61

• References & Citations :

  [1]Gonzalez S, et al. Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage. Neurobiol Dis. 2022 Jan;162:105563.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  TrkB; TrkC

• CAS Number :

  [1627834-10-9]