ZCL278-13C

• Description:

  ZCL278-13C is 13C-labeled ZCL278 (HY-13963) . ZCL278 is a selective Cdc42 modulator that directly binds to Cdc42 and inhibits its functions with Kd of 11.4 μM for Cdc42-ZCL278 affinity in surface plasmon resonance (SPR) experiment.

• UNSPSC:

  12352005

• Target:

  Endogenous Metabolite; Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Cancer; Infection

• Smiles:

  S=C(NC1=CC=C(C=C1)S(=O)(NC2=NC(C)=CC(C)=N2)=O)N[13C](COC3=CC=C(C=C3Cl)Br)=O

• Molecular Formula:

  C20 13CH19BrClN5O4S2

• Molecular Weight:

  585.89

• References & Citations:

  [1]Friesland A, et al. Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility. Proc Natl Acad Sci U S A. 2013 Jan 22;110 (4) :1261-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported