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CYP4Z1-IN-2

CAT: 0804-HY-139002Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139002Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYP4Z1-IN-2 (compound 7) is a reversible inhibitor of CYP4Z1 (Ki=2.2 μM), which inhibits the production of 14,15-EET in breast cancer cells. CYP4Z1-IN-2 inhibits the CYP4Z1-mediated Luc-BE O-debenzylation reaction with an IC50 of 5.9 μM[1].
CAS Number
2428734-45-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(O)CCCCCCCNN1N=NC2=CC=CC=C21
Molecular Formula
C14H20N4O2
Molecular Weight
276.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kowalski JP, et al. Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1. J Med Chem. 2020 May 14;63 (9) :4824-4836.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP4

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