Phosphoramide mustard (cyclohexanamine) (Standard)

• Description :

  Phosphoramide mustard (cyclohexanamine) (Standard) is the analytical standard of Phosphoramide mustard (cyclohexanamine) . This product is intended for research and analytical applications. Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage[1][2].

• UNSPSC :

  12352211

• Target :

  DNA Alkylator/Crosslinker; Drug Metabolite; Reference Standards

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

• Field of Research :

  Cancer

• Smiles :

  O=P(N(CCCl)CCCl)(N)O.NC1CCCCC1

• Molecular Formula :

  C10H24Cl2N3O2P

• Molecular Weight :

  320.20

• References & Citations :

  [1]Shanthi Ganesan, et al. Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells. Toxicol Appl Pharmacol. 2015 Feb 1; 282 (3) : 252–258.|[2]S Genka, et al. Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat. Cancer Chemother Pharmacol. 1990;27 (1) :1-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [1566-15-0]