Phosphoramide mustard (cyclohexanamine) (Standard)

CAT: 0804-HY-137316ARSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-137316ARSize:1 Each
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Description
Phosphoramide mustard (cyclohexanamine) (Standard) is the analytical standard of Phosphoramide mustard (cyclohexanamine) . This product is intended for research and analytical applications. Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage[1][2].
CAS Number
[1566-15-0]
UNSPSC
12352211
Target
DNA Alkylator/Crosslinker; Drug Metabolite; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=P(N(CCCl)CCCl)(N)O.NC1CCCCC1
Molecular Formula
C10H24Cl2N3O2P
Molecular Weight
320.20
References & Citations
[1]Shanthi Ganesan, et al. Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells. Toxicol Appl Pharmacol. 2015 Feb 1; 282 (3) : 252–258.|[2]S Genka, et al. Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat. Cancer Chemother Pharmacol. 1990;27 (1) :1-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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