Fluvastatin lactone

• Description :

  Fluvastatin lactone, a lactone form of Fluvastatin (HY-14664), induces myotoxicity in human skeletal muscle cells[1].

• CAS Number :

  [94061-83-3]

• UNSPSC :

  12352005

• Target :

  Drug Derivative; HMG-CoA Reductase (HMGCR)

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Field of Research :

  Cancer; Cardiovascular Disease

• Smiles :

  O=C1C[C@H](O)C[C@@H](/C=C/C(N2C(C)C)=C(C3=CC=C(F)C=C3)C4=C2C=CC=C4)O1

• Molecular Formula :

  C24H24FNO3

• Molecular Weight :

  393.45

• References & Citations :

  [1]Skottheim IB, et al. Statin induced myotoxicity: the lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro. Eur J Pharm Sci. 2008 Apr 23;33 (4-5) :317-25.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported