Fluvastatin lactone

CAT: 0804-HY-137213Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-137213Size:1 Each
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Description
Fluvastatin lactone, a lactone form of Fluvastatin (HY-14664), induces myotoxicity in human skeletal muscle cells[1].
CAS Number
[94061-83-3]
UNSPSC
12352005
Target
Drug Derivative; HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C1C[C@H](O)C[C@@H](/C=C/C(N2C(C)C)=C(C3=CC=C(F)C=C3)C4=C2C=CC=C4)O1
Molecular Formula
C24H24FNO3
Molecular Weight
393.45
References & Citations
[1]Skottheim IB, et al. Statin induced myotoxicity: the lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro. Eur J Pharm Sci. 2008 Apr 23;33 (4-5) :317-25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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