Products for Research Use Only
RegisterLogin

Fluvastatin

CAT: 0804-HY-14664-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14664-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
CAS Number
93957-54-1
Product Name Alternative
XU 62-320 (free acid)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Fluvastatin.html
Purity
98.49
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C[C@H](O)C[C@H](O)/C=C/C(N1C(C)C)=C(C2=CC=C(F)C=C2)C3=C1C=CC=C3
Molecular Formula
C24H26FNO4
Molecular Weight
411.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Makabe S, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213 (2) :377-84.|[2]Wu Zhang, et al. Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway. Indian J Exp Biol. 2010 Dec;48 (12) :1167-74.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
ACS Omega. 2025 Oct 29;10 (44) :52562–52575.|Biochem Biophys Res Commun. 2020 Feb 19;522 (4) :862-868.|Biomed Pharmacother. 2024 Jun:175:116644.|bioRxiv. 2024 October 04.|Cell Prolif. 2021 Jan;54 (1) :e12953.|Cell Rep Med. 2024 May 29:101592.|Chem Eng J. 1 January 2023, 138972.|Front Cell Dev Biol. 2020 May 28;8:404.|Front Oncol. 2021 May 10:11:595285.|Pharmacol Res. 2023 Apr:190:106724.|PLoS Biol.2024 May 28;22 (5) :e3002621.|Proteomics. 2023 Aug;23 (16) :e2300041.|SSRN. 2025 Jul 7.|FEBS Open Bio. 2025 Aug 8.|Front Bioeng Biotechnol. 2022 Mar 17;10:826093.|Mol Med Rep. 2018 Mar;17 (3) :3944-3950.|Pathogens. 2021 Mar 2;10 (3) :283.|Phytother Res. 2025 May;39 (5) :1930-1945.

Related Products

CatalogName
HY-N14989Fluostatin A
HY-N15181Fluostatin B
HY-N14989A-01Fluostatin A (sodium)

Alternative Products

CatalogName
A3419-5.1Fluvastatin
A4363-5.1Fluvastatin Sodium
413340Fluvastatin potassium
FF65027-01Fluvastatin lactone

Popular Products