BC8-15

• Description :

  BC8-15 is a PDE inhibitor with IC50 values of 0.28, 0.22, and 6.46 µM for inhibiting PDE8A, PDE4A, and PDE7A, respectively. BC8-15 can enhance steroidogenesis in mouse Leydig cells[1].

• CAS Number :

  [950385-77-0]

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Smiles :

  O=C(C1=CC(NC2=NC3=C(C4=NN=C(CC)N24)C=CC=C3)=CC=C1)O

• Molecular Formula :

  C18H15N5O2

• Molecular Weight :

  333.34

• References & Citations :

  [1]Demirbas D, et al. A yeast-based chemical screen identifies a PDE inhibitor that elevates steroidogenesis in mouse Leydig cells via PDE8 and PDE4 inhibition[J]. PLoS One, 2013, 8 (8) : e71279.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PDE4; PDE7; PDE8