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SM-102 (GMP)

CAT: 0804-HY-134541GSize: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-134541GSize:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SM-102 (GMP) is SM-102 (HY-134541) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs) . SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines[1][2].
CAS Number
[2089251-47-6]
UNSPSC
12352211
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCO)CCCCCC(OCCCCCCCCCCC)=O
Molecular Formula
C44H87NO5
Molecular Weight
710.17
References & Citations
[1]Escalona-Rayo O, et al. In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy. Biomed Pharmacother. 2023 Sep;165:115065.|[2]Cho HY, et al. Effective Perturbations on the Amplitude and Hysteresis of Erg-Mediated Potassium Current Caused by 1-Octylnonyl 8-[ (2-hydroxyethyl) [6-oxo-6 (undecyloxy) hexyl]amino]-octanoate (SM-102), a Cationic Lipid. Biomedicines. 2021 Oct 1;9 (10) :1367. |[3]Mashima R, et al. Lipid Nanoparticles: A Novel Gene Delivery Technique for Clinical Application. Curr Issues Mol Biol. 2022 Oct 19;44 (10) :5013-5027.|[4]McKenzie RE, et al. mRNA Synthesis and Encapsulation in Ionizable Lipid Nanoparticles. Curr Protoc. 2023 Sep;3 (9) :e898.
Shipping Conditions
Blue Ice
Storage Conditions
Kept at -20 ± 5°C under an inert atmosphere.
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported

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