SET7-IN-DC21

CAT: 0804-HY-133567Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-133567Size:1 Each
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Description
SET7-IN-DC21 is a selective, potent SET7 inhibitor (IC50 = 15.93 μM; KD = 18.00 μM) . SET7-IN-DC21 has good selectivity for several other epigenetic targets, such as SUV39H1, G9a, NSD1, DOT1L and MOF. SET7-IN-DC21 can be used for the researches of cancer, infection, inflammation, metabolic and cardiovascular disease, such as breast cancer[1].
CAS Number
[2567886-53-5]
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C(C=C1)C(C2=CC=C(C(OC)=O)O2)=CC1=O
Molecular Formula
C12H8O5
Molecular Weight
232.19
References & Citations
[1]Hou Z, et al. Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors. Bioorg Med Chem Lett. 2020 May 1;30 (9) :127061.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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