SET7-IN-DC21

• Description:

  SET7-IN-DC21 is a selective, potent SET7 inhibitor (IC50 = 15.93 μM; KD = 18.00 μM) . SET7-IN-DC21 has good selectivity for several other epigenetic targets, such as SUV39H1, G9a, NSD1, DOT1L and MOF. SET7-IN-DC21 can be used for the researches of cancer, infection, inflammation, metabolic and cardiovascular disease, such as breast cancer[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase

• Related Pathways:

  Epigenetics

• Field of Research:

  Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

• Smiles:

  O=C(C=C1)C(C2=CC=C(C(OC)=O)O2)=CC1=O

• Molecular Formula:

  C12H8O5

• Molecular Weight:

  232.19

• References & Citations:

  [1]Hou Z, et al. Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors. Bioorg Med Chem Lett. 2020 May 1;30 (9) :127061.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2567886-53-5]