DC271

CAT: 0804-HY-D1190Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-D1190Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DC271 is a RAR agonist that can be considered a retinoid, eliciting cellular responses consistent with the endogenous retinoid ATRA and the synthetic retinoid EC23. DC271 binds to retinoid protein machinery, including CRABPII, to translocate the endogenous retinoid ATRA into the nucleus[1].
CAS Number
[198696-03-6]
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dc271.html
Purity
97.7
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(C#CC2=CC3=C(N(C(C)C)CCC3(C)C)C=C2)C=C1
Molecular Formula
C23H25NO2
Molecular Weight
347.45
References & Citations
[1]Chisholm DR, et al. Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways. ACS Chem Biol. 2019 Mar 15;14 (3) :369-377.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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