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MS-153

CAT: 0804-HY-133177-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133177-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MS-153 is a glutamate transporter activator that can be used as a neuroprotective agent[1][2].
CAS Number
130775-79-0
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
EAAT
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Smiles
C[C@@H]1CC=NN1C(C2=CN=CC=C2)=O
Molecular Formula
C10H11N3O
Molecular Weight
189.21
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Shimada F, et al. The neuroprotective agent MS-153 stimulates glutamate uptake. Eur J Pharmacol. 1999 Dec 15;386 (2-3) :263-70.|[2]Nakagawa T, et al. Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator. Eur J Pharmacol. 2001 May 4;419 (1) :39-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

Chemical Information

(R)-(5-Methyl-4,5-dihydro-1H-pyrazol-1-YL)(pyridin-3-YL)methanone
CAS Number130775-79-0
PubChem CID10313453
IUPAC Name[(3R)-3-methyl-3,4-dihydropyrazol-2-yl]-pyridin-3-ylmethanone
Molecular FormulaC10H11N3O
Molecular Weight189.21
XLogP0.2
Topological Polar Surface Area45.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count14
Formal Charge0
Complexity252
SMILES
C[C@@H]1CC=NN1C(=O)C2=CN=CC=C2
InChI
InChI=1S/C10H11N3O/c1-8-4-6-12-13(8)10(14)9-3-2-5-11-7-9/h2-3,5-8H,4H2,1H3/t8-/m1/s1
InChIKey
KKMMIKKVFRCZBO-MRVPVSSYSA-N
Chemical Structure
2D Structure
2D structure of (R)-(5-Methyl-4,5-dihydro-1H-pyrazol-1-YL)(pyridin-3-YL)methanone
CAS: 130775-79-0
CID: 10313453
Formula: C10H11N3O
MW: 189.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight189.21
XLogP30.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass189.090211983
Monoisotopic Mass189.090211983
Topological Polar Surface Area45.6 Ų
Heavy Atom Count14
Formal Charge0
Complexity252
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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