Iso-OMPA (Standard)

• Description :

  Iso-OMPA (Standard) is the analytical standard of Iso-OMPA. This product is intended for research and analytical applications. Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE) . Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE) [1][2][3].

• UNSPSC :

  12352100

• Target :

  Cholinesterase (ChE) ; Reference Standards

• Related Pathways :

  Neuronal Signaling; Others

• Field of Research :

  Neurological Disease

• Smiles :

  O=P(NC(C)C)(NC(C)C)OP(NC(C)C)(NC(C)C)=O

• Molecular Formula :

  C12H32N4O3P2

• Molecular Weight :

  342.36

• References & Citations :

  [1]Rodríguez-Fuentes G, et al. Characterization of cholinesterase activity from different tissues of Nile tilapia (Oreochromis niloticus) . Mar Environ Res. 2004 Aug-Dec;58 (2-5) :505-9.|[2]Z Grubic, et al. Iso-OMPA-induced potentiation of soman toxicity in rat correlates with the inhibition of plasma carboxylesterases. Arch Toxicol. 1988;62 (5) :398-9.|[3]X Norel, et al. Degradation of acetylcholine in human airways: role of butyrylcholinesterase. Br J Pharmacol. 1993 Apr;108 (4) :914-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [513-00-8]