3-Hydroxycoumarin (Standard)

• Description:

  3-Hydroxycoumarin (Standard) is the analytical standard of 3-Hydroxycoumarin. This product is intended for research and analytical applications. 3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage[1][2].

• UNSPSC:

  12352100

• Target:

  Lipoxygenase; Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Others

• Smiles:

  O=C1C(O)=CC2=CC=CC=C2O1

• Molecular Formula:

  C9H6O3

• Molecular Weight:

  162.14

• References & Citations:

  [1]Born SL, et al. Synthesis and reactivity of coumarin 3,4-epoxide. Drug Metab Dispos. 1997;25 (11) :1318‐1324.|[2]Alavi SJ, Sadeghian H, Seyedi SM, Salimi A, Eshghi H. A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarin. Chem Biol Drug Des. 2018;91 (6) :1125‐1132.|[3]Asthana S, et al. Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase. J Agric Food Chem. 2015;63 (32) :7236‐7244.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  939-19-5