GSK-214096

CAT: 0804-HY-123884Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123884Size:1 Each
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Description
GSK-214096 is a selective CCR5 antagonist and an inhibitor of HIV-1 entry. GSK-214096 inhibits HIV-1 glycoprotein 120 (gp120) [1].
CAS Number
[716354-87-9]
UNSPSC
12352005
Target
CCR; HIV
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=S(C1=CC=C(Cl)C(C(N2CCC(CCN3[C@@]4([H])C[C@H](N5C(C)=NC6=CC=CC=C56)C[C@]3([H])CC4)(C7=CC=CC(F)=C7)CC2)=O)=C1Cl)(NC(C)(C)C)=O
Molecular Formula
C39H46Cl2FN5O3S
Molecular Weight
754.78
References & Citations
[1]Wieslaw Kazmierski, et al., (2014) . Biological and Structural Characterization of Rotamers of C-C Chemokine Receptor Type 5 (CCR5) Inhibitor GSK214096. ACS Medicinal Chemistry Letters 5 (12) :1296-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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