SCH 350581

• Description :

  SCH 350581 (AD-101) is a CCR5 antagonist. SCH 350581 inhibits HIV-1 replication, viral entry into cells, and the binding of gp120 to cell lines in primary lymphocytes[1].

• Product Name Alternative :

  AD-101

• UNSPSC :

  12352005

• Target :

  CCR

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Smiles :

  O=C(C1=C(C)C=CN=C1C)N2CCC(N3C[C@H](C)N([C@H](C4=CC=C(C(F)(F)F)C=C4)C)CC3)(C)CC2

• Molecular Formula :

  C28H37F3N4O

• Molecular Weight :

  502.61

• References & Citations :

  [1]Tsamis F, et al. Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry. J Virol. 2003 May;77 (9) :5201-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [306293-36-7]