SCH 350581

• Description:

  SCH 350581 (AD-101) is a CCR5 antagonist. SCH 350581 inhibits HIV-1 replication, viral entry into cells, and the binding of gp120 to cell lines in primary lymphocytes[1].

• Product Name Alternative:

  AD-101

• UNSPSC:

  12352005

• Target:

  CCR

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Smiles:

  O=C (C1=C (C) C=CN=C1C) N2CCC (N3C[C@H] (C) N ([C@H] (C4=CC=C (C (F) (F) F) C=C4) C) CC3) (C) CC2

• Molecular Formula:

  C28H37F3N4O

• Molecular Weight:

  502.61

• References & Citations:

  [1]Tsamis F, et al. Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry. J Virol. 2003 May;77 (9) :5201-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  306293-36-7