MK-761 (TFA)

CAT: 0804-HY-123449A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-123449A-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-761 TFA is a potent and orally active β2-adrenergic blocker. MK-761 TFA shows antihypertensive and positive inotropic effects. MK-761 TFA shows vasodilating properties[1].
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
99.93
Smiles
N#CC1=CC=CN=C1OC[C@H](CNC(C)(C)C)O.O=C(C(F)(F)F)O
Molecular Formula
C15H20F3N3O4
Molecular Weight
363.33
References & Citations
[1]Scriabine A, et al. Antihypertensive and cardiac effects of two novel beta-adrenoceptor blocking drugs. Experientia. 1979 Dec 15;35 (12) :1634-7.|[2]C.S. Sweet, et al. Peripheral Vasodilator and β-Adrenoceptor Blocking Properties of Several β-Adrenoceptor Antagonists. Clinical and Experimental Hypertension. 2009, 449-471.|[3]Sweet CS, et al. Beta adrenoceptor blocking properties of MK-761. J Pharmacol Exp Ther. 1979 Oct;211 (1) :195-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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