BGC20-761

CAT: 0804-HY-21995-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-21995-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor Ki values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM) . BGC20-761, can enhance long-term memory. BGC20-761 has potential utility as an antipsychotic agent[1].
CAS Number
[17375-63-2]
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bgc20-761.html
Solubility
10 mM in DMSO
Smiles
CN(C)CCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3
Molecular Formula
C19H22N2O
Molecular Weight
294.39
References & Citations
[1]Ellen S Mitchell, et al. BGC20-761, a novel tryptamine analog, enhances memory consolidation and reverses scopolamine-induced memory deficit in social and visuospatial memory tasks through a 5-HT6 receptor-mediated mechanism. Neuropharmacology. 2006 Mar;50 (4) :412-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor;5-HT6 Receptor; D2 Receptor; MUC2; α-1 microglobulin

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