CPA-7

CAT: 0804-HY-122759Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-122759Size:1 Each
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Description
CPA7 is a novel Stat3 inhibitor. CPA7 downregulates survivin, Bcl-XL, and Mcl-1. CPA7 induces Apoptosis. CPA7 enhances the radiosensitivity of prostate cancer. CPA7 has anti-cancer effects against prostate cancer[1][2].
CAS Number
[16961-77-6]
UNSPSC
12352100
Target
Apoptosis; Bcl-2 Family; STAT; Survivin
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=[N-]([Pt+4]([Cl-])([Cl-])([NH3])([NH3])[Cl-])=O
Molecular Formula
Cl3H6N3O2Pt
Molecular Weight
381.51
References & Citations
[1]Sekharam M, et al. CPA7, a novel Stat3 inhibitor radiosensitizes prostate cancer cells. International Journal of Radiation Oncology, Biology, Physics, 2005, 63: S483.|[2]Liang M, et al. CPA-7 influences immune profile and elicits anti-prostate cancer effects by inhibiting activated STAT3. BMC Cancer. 2016 Jul 19;16:504.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bcl-xL; Mcl-1; STAT3

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