TAK-100

CAT: 0804-HY-122188Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-122188Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

TAK-100 is a selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor with an IC50 of 5.3 nM. TAK-100 hass little or no inhibitory effects on other dipeptidyl peptidase members. TAK-100 can be used for the study of diabetes[1].

CAS Number

[907609-33-0]

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=C(O)CC1=C(C2=CC=C(C)C=C2)C(CN)=C(CC(C)(C)C)N=C1CC

Molecular Formula

C22H30N2O2

Molecular Weight

354.49

References & Citations

[1]Miyamoto Y, et al.. Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor. J Med Chem. 2011 Feb 10;54 (3) :831-50.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

DPP-4

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