TAK-100

• Description:

  TAK-100 is a selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor with an IC50 of 5.3 nM. TAK-100 hass little or no inhibitory effects on other dipeptidyl peptidase members. TAK-100 can be used for the study of diabetes[1].

• UNSPSC:

  12352005

• Target:

  Dipeptidyl Peptidase

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(O)CC1=C(C2=CC=C(C)C=C2)C(CN)=C(CC(C)(C)C)N=C1CC

• Molecular Formula:

  C22H30N2O2

• Molecular Weight:

  354.49

• References & Citations:

  [1]Miyamoto Y, et al.. Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor. J Med Chem. 2011 Feb 10;54 (3) :831-50.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• Isoform:

  DPP-4

• CAS Number:

  907609-33-0