BMS 182874 (Standard)

• Description:

  BMS 182874 (Standard) is the analytical standard of BMS 182874. This product is intended for research and analytical applications. BMS 182874 is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 μM, Ki of 0.055 μM. BMS 182874 reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research[1].

• UNSPSC:

  12352100

• Target:

  Endothelin Receptor; Reference Standards

• Related Pathways:

  GPCR/G Protein; Others

• Field of Research:

  Metabolic Disease; Cardiovascular Disease

• Smiles:

  O=S(C1=C2C=CC=C(C2=CC=C1)N(C)C)(NC3=C(C(C)=NO3)C)=O

• Molecular Formula:

  C17H19N3O3S

• Molecular Weight:

  345.42

• References & Citations:

  [1]Abdullaha M, et.al. Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship. ACS Omega. 2023 May 9;8 (20) :17591-17608.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [153042-42-3]