BMS-309403 (Standard)

• Description :

  BMS-309403 (Standard) is the analytical standard of BMS-309403. This product is intended for research and analytical applications. BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of [1][2][3].

• UNSPSC :

  12352005

• Target :

  FABP; Reference Standards

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Field of Research :

  Metabolic Disease; Cardiovascular Disease

• Smiles :

  O=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1

• Molecular Formula :

  C31H26N2O3

• Molecular Weight :

  474.55

• References & Citations :

  [1]Sulsky R, et al. Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP) . Bioorg Med Chem Lett. 2007 Jun 15;17 (12) :3511-5.|[2]Lin W, et al. BMS309403 stimulates glucose uptake in myotubes through activation of AMP-activated protein kinase. PLoS One. 2012;7 (8) :e44570.|[3]Lee MY, et al. Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells. Br J Pharmacol. 2011 Apr;162 (7) :1564-76.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [300657-03-8]