BL-122

CAT: 0804-HY-114218Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-114218Size:1 Each
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Description
BL-122 is a selective phosphodiesterase-5 (PDE-5) inhibitor. BL-122 can increase the level of cGMP in the tissue, promote the expression of nitric oxide (NO), and mediate the relaxation of smooth muscle. BL-122 can be used for the researches of inflammation, immunology and cardiovascular disease, such as asthma and hypertension[1].
CAS Number
[1220393-12-3]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C([C@@H](CC1=C(C(C2=CC=C(OCO3)C3=C2)=O)NC4=C1C=CC=C4)N5)N(C)CC5=O
Molecular Formula
C22H19N3O5
Molecular Weight
405.40
References & Citations
[1]Sérgio Luiz SACURAI, et al. Compounds derived from 2- (3-methylenedioxy) -benzoyl indol. WO2010037190A1. 2010-04-08.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE5

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