DOPE (GMP Like)

• Description:

  DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].

• Product Name Alternative:

  Dioleoylphosphatidylethanolamine (GMP Like) ; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)

• UNSPSC:

  12352211

• Target:

  Endogenous Metabolite; Liposome

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=P(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)(OCCN)O

• Molecular Formula:

  C41H78NO8P

• Molecular Weight:

  744.03

• References & Citations:

  [1]Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24 (3) :263-268.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  GMP Small Molecules

• Clinical Information:

  No Development Reported

• CAS Number:

  [4004-05-1]