DOPE (GMP Like)

• Description :

  DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].

• Product Name Alternative :

  Dioleoylphosphatidylethanolamine (GMP Like) ; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)

• UNSPSC :

  12352211

• Target :

  Endogenous Metabolite; Liposome

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=P(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)(OCCN)O

• Molecular Formula :

  C41H78NO8P

• Molecular Weight :

  744.03

• References & Citations :

  [1]Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24 (3) :263-268.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  GMP Small Molecules

• Clinical Information :

  No Development Reported

• CAS Number :

  [4004-05-1]