VA-111913

• Description:

  VA-111913 (VT-913) is a vasopressin receptor V1A antagonist (Ki = 1.74 nM) . VA-111913 reduces uterine contractions and improves uterine blood flow by inhibiting vasopressin, thereby alleviating dysmenorrhea. VA-111913 can be used for research on menstrual pain[1].

• Product Name Alternative:

  VT-913

• UNSPSC:

  12352005

• Target:

  Vasopressin Receptor

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Neurological Disease; Cardiovascular Disease

• Smiles:

  O=C(C1CC1)NCC2=CC=C(C(N3CC4=C(N(C)N=C4)NC5=CC(Cl)=CC=C35)=O)C=C2F

• Molecular Formula:

  C23H21ClFN5O2

• Molecular Weight:

  453.90

• References & Citations:

  [1]Cole P, et al. Medicinal chemistry Highlights from the 239th American Chemical Society National Meeting & Exposition. Drugs of the Future. 2010;35 (6) :503-15.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  V1a Receptor

• CAS Number:

  [877856-17-2]