(R) -Equol (Standard)

• Description:

  (R) -Equol (Standard) is the analytical standard of (R) -Equol. This product is intended for research and analytical applications. (R) -Equol is an agonist of both ERα and ERβ with Kis of 27.4 and 15.4 nM, respectively.

• UNSPSC:

  12352100

• Target:

  Estrogen Receptor/ERR; Reference Standards

• Related Pathways:

  Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer

• Smiles:

  OC1=CC=C2C[C@H] (C3=CC=C (O) C=C3) COC2=C1

• Molecular Formula:

  C15H14O3

• Molecular Weight:

  242.27

• References & Citations:

  [1]Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81 (5) :1072-9.|[2]Magee PJ, et al. Daidzein, R- (+) equol and S- (-) equol inhibit the invasion of MDA-MB-231 breast cancer cells potentially via the down-regulation of matrix metalloproteinase-2. Eur J Nutr. 2014 Feb;53 (1) :345-50.|[3]Brown NM, et al. The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer. Carcinogenesis. 2010 May;31 (5) :886-93.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  221054-79-1