(-) - (S) -Equol (Standard)

• Description :

  (-) - (S) -Equol (Standard) is the analytical standard of (-) - (S) -Equol. This product is intended for research and analytical applications. (-) - (S) -Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite; Estrogen Receptor/ERR; Reference Standards

• Related Pathways :

  Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Cancer; Metabolic Disease; Neurological Disease

• Purity :

  98.90

• Smiles :

  OC1=CC=C2C[C@H](COC2=C1)C3=CC=C(C=C3)O

• Molecular Formula :

  C15H14O3

• Molecular Weight :

  242.27

• References & Citations :

  [1]Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81 (5) :1072-9.|[2]Lu Z, et al. S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway. Curr Cancer Drug Targets. 2016;16 (5) :455-65.|[3]Horiuchi H, et al. S-equol nantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells. J Nutr Sci Vitaminol (Tokyo) . 2014;60 (4) :291-6.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, sealed storage, away from light and moisture

• Scientific Category :

  Reference Standards

• CAS Number :

  [531-95-3]