(-) - (S) -Equol (Standard)

CAT: 0804-HY-100583R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100583R-01Size:5 mg
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Description
(-) - (S) -Equol (Standard) is the analytical standard of (-) - (S) -Equol. This product is intended for research and analytical applications. (-) - (S) -Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.
CAS Number
[531-95-3]
UNSPSC
12352005
Target
Endogenous Metabolite; Estrogen Receptor/ERR; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Purity
98.90
Smiles
OC1=CC=C2C[C@H](COC2=C1)C3=CC=C(C=C3)O
Molecular Formula
C15H14O3
Molecular Weight
242.27
References & Citations
[1]Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81 (5) :1072-9.|[2]Lu Z, et al. S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway. Curr Cancer Drug Targets. 2016;16 (5) :455-65.|[3]Horiuchi H, et al. S-equol nantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells. J Nutr Sci Vitaminol (Tokyo) . 2014;60 (4) :291-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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