Atomoxetine-d5

• Description :

  Atomoxetine-d5 (Tomoxetine-d5) is deuterium labeled Atomoxetine. Atomoxetine (Tomoxetine) is a selective noradrenaline reuptake inhibitor with Ki values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine (Tomoxetine) increases of DAEX and NEEX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine (Tomoxetine) is a potent Na+ channels (VGSCs) blocker. Atomoxetine (Tomoxetine) can be used for attention-deficit hyperactivity disorder (ADHD) research[1][2][3].

• Product Name Alternative :

  Tomoxetine-d5; (R) -Tomoxetine-d5

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Neurological Disease; Cancer

• Smiles :

  CC(C=CC=C1)=C1O[C@@H](C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])CCNC

• Molecular Formula :

  C17H16D5NO

• Molecular Weight :

  260.39

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1129478-03-0]