BC-1175

• Description:

  BC-1175 (CB-181963) is a novel cephalosporin and antibacterial agent. CB-181963 displays strong binding to altered PBP 2a. CB-181963 demonstrates marked efficacy against MRSA, Klebsiella pneumoniae, Streptococcus pneumoniae, and Escherichia coli[1][2].

• Product Name Alternative:

  CB-181963

• UNSPSC:

  12352005

• Target:

  Bacterial; Penicillin-binding protein (PBP)

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  OC(C1=C(/C=N/N(C)C(N2CCNCC2)=N)CS[C@@]([C@@H]3NC(/C(C4=NSC(N)=N4)=N\OCF)=O)([H])N1C3=O)=O

• Molecular Formula:

  C19H24FN11O5S2

• Molecular Weight:

  569.59

• References & Citations:

  [1]Miller K, et al. Antistaphylococcal activity of the novel cephalosporin CB-181963 (CAB-175) . J Antimicrob Chemother. 2005 Apr;55 (4) :579-82.|[2]Huang V, et al. In vitro activities of a novel cephalosporin, CB-181963 (CAB-175), against methicillin-susceptible or -resistant Staphylococcus aureus and glycopeptide-intermediate susceptible staphylococci. Antimicrob Agents Chemother. 2004 Jul;48 (7) :2719-23.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [635292-67-0]