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BC-1293

CAT: 0931-T89425-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T89425-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1219395-86-4
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Purity
0.984
Bioactivity
BC-1293 is an inhibitor of the E3 ligase subunit FBXO24 that acts by disrupting the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2) . BC-1293 treatment results in increased levels of DARS2, showing its capacity to stabilize this essential enzyme. Furthermore, BC-1293 elevates levels of cytokines including IL-1β, IL-9, MIP-2, and TNF-α in murine models, thereby demonstrating immunostimulatory activity with potential relevance to immune modulation research.
Smiles
O=C(N1CC=C(C=2C=CC=CC2)CC1)C(NS(=O)(=O)C=3C=C(C=CC3C)C4=NOC(=N4)C5CC5)C
Molecular Formula
C26H28N4O4S
Molecular Weight
492.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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