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BRL 34778

CAT: 0804-HY-106820Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106820Size:1 Each
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Description
BRL 34778 is a potent, selective and orally active dopamine D2 receptor antagonist with a Ki of 2.14 nM. BRL 34778 exhibits antipsychotic activity with low activity for extrapyramidal effects and sedation. BRL 34778 can be used for the research of neurological disease, such as schizophrenia[1].
CAS Number
86580-77-0
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1=C(C=C(N)C(Cl)=C1)OC)N[C@@H](C[C@@H]2CCC3)C[C@@H]3N2CC4=CC=C(F)C=C4
Molecular Formula
C23H27ClFN3O2
Molecular Weight
431.93
References & Citations
[1]Brown F, et al. The selective dopamine antagonist properties of BRL 34778: a novel substituted benzamide. Psychopharmacology (Berl) . 1988;94 (3) :350-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor

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