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DQ 2556

CAT: 0804-HY-106095Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106095Size:1 Each
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Description
DQ 2556 is a semi-synthetic cephalosporin antibiotic. DQ-2556 exhibits significant activity against both Gram-positive and Gram-negative bacteria, particularly Gram-positive bacteria and Enterobacteriaceae infections. DQ 2556 exerts its bactericidal effect by interfering with cell division. DQ-2556 has a strong affinity for the penicillin-binding proteins (PBPs) of Escherichia coli: PBP1A/1B (IC₅₀ = 0.57-0.73 μg/mL) and PBP3 (IC₅₀ = 0.088 μg/mL) . DQ-2556 demonstrates significant in vivo protective effects. DQ-2556 can be used in the development of injectable cephalosporins[1][2].
CAS Number
102253-70-3
UNSPSC
12352005
Target
Antibiotic; Bacterial; Penicillin-binding protein (PBP)
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
[O-]C(C1=C(C[N+]2=CC=C(C3=CN=CO3)C=C2)CS[C@@]([C@@H]4NC(/C(C5=CSC(N)=N5)=N\OC)=O)([H])N1C4=O)=O
Molecular Formula
C22H19N7O6S2
Molecular Weight
541.56
References & Citations
[1]Fujimoto T, et al. In vitro activity of DQ-2556, a new cephalosporin. Antimicrob Agents Chemother. 1986 Oct;30 (4) :611-3. |[2]Ishida Y, et al. In vitro and in vivo activity of DQ-2556, a new cephalosporin. Chemotherapy. 1995 Jan-Feb;41 (1) :5-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β-lactam

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