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DQ-BSA-RED

CAT: 0804-HY-D2449-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-D2449-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DQ-BSA-Red is a bovine serum albumin labeled with a red fluorescent dye that can be used to detect lysosomal activity. The excitation wavelength and emission wavelength of DQ-BSA-Red are 590 nm and 620 nm, respectively. The BSA molecule in DQ-BSA-Red is labeled with high concentration of red fluorescent dye in multiple sites, which shows high fluorescence self-inhibition. Once DQ-BSA-RED enters the lysosome, DQ-BSA is cleaved by lysosomal proteases, resulting in unquenched and released fluorescent fragments, emitting bright fluorescence. Inactivated lysosomes are unable to degrade the BSA protein and thus have a lower or even no fluorescent signal[1].
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dq-bsa-red.html
Smiles
[DQ-BSA-RED]
References & Citations
[1]Marwaha R, et al. DQ-Red BSA Trafficking Assay in Cultured Cells to Assess Cargo Delivery to Lysosomes. Bio Protoc. 2017 Oct 5;7 (19) :e2571.|[2]Frost LS, et al. The Use of DQ-BSA to Monitor the Turnover of Autophagy-Associated Cargo. Methods Enzymol. 2017;587:43-54.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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