Pibrozelesin (hydrobromide)

• Description:

  Pibrozelesin hydrobromide is a hydrolytic prodrug of Carzelesin (HY-19601) . Pibrozelesin hydrobromide has an anticancer activity. Carzelesin is a cyclopropylpyrroloindole precursor molecule and effectively inhibits tumor growth. Carzelesin may be used in cancer research[1].

• UNSPSC:

  12352005

• Target:

  Drug Intermediate

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Smiles:

  O=C (C (C1=C (C (CN2C (C3=CC4=C (N3) C (OC) =C (OC) C (OC) =C4) =O) CBr) C2=C5) =C (C) NC1=C5OC (N6CCN (CC6) C) =O) OC.Br

• Molecular Formula:

  C32H37Br2N5O8

• Molecular Weight:

  779.47

• References & Citations:

  [1]Felber JG, et al. 40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs. JACS Au. 2022 Nov 15;2 (12) :2636-2644.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  148778-32-9