Ro26-4550 (TFA)

• Description:

  Ro26-4550 TFA is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM[1].

• UNSPSC:

  12352005

• Target:

  Interleukin Related

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(OC)[C@H](CC1=CC=C(C#CC2=CC=CC=C2)C=C1)NC(C[C@@H]3CN(C(N)=N)CCC3)=O.O=C(O)C(F)(F)F

• Molecular Formula:

  C28H31F3N4O5

• Molecular Weight:

  560.56

• References & Citations:

  [1]Braisted AC, et al. Discovery of a potent small molecule IL-2 inhibitor through fragment assembly. J Am Chem Soc. 2003 Apr 2;125 (13) :3714-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1217448-66-2