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Cdc7-IN-1 (Standard)

CAT: 0804-HY-101523RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101523RSize:1 Each
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Description
Cdc7-IN-1 (Standard) is the analytical standard of Cdc7-IN-1. This product is intended for research and analytical applications. Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].
CAS Number
1402055-25-7
Target
CDK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O=C1C(C(OCC)=O)=C(NC2=C(Cl)C=CC=C2)O/C1=C\C3=CNC4=C3C=CC=N4
Molecular Formula
C21H16ClN3O4
Molecular Weight
409.82
References & Citations
[1]Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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