MC-207110

• Description:

  MC-207110 is a broad-spectrum efflux pump inhibitor. MC-207110 is active against all three known Mex efflux pumps from P. aeruginosa and their close Escherichia coli efflux pump homolog (AcrAB-TolC) . MC-207110 can decrease the intrinsic resistance of P. aeruginosa to fluoroquinolones. MC-207110 can be used for the research of infection [1].

• UNSPSC:

  12352005

• Hazard Statement:

  H301-H315-H319-H335

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C([C@H](CCCNC(N)=N)NC([C@H](CC1=CC=CC=C1)N)=O)NC2=CC(C=CC=C3)=C3C=C2

• Molecular Formula:

  C25H30N6O2

• Molecular Weight:

  446.54

• Precautions:

  P264-P270-P330-P405-P501

• References & Citations:

  [1]Lomovskaya O, et al. Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Chemother. 2001 Jan;45 (1) :105-16.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Citation 01:

  ACS Infect Dis. 2024 Feb 9;10 (2) :541-552.|Microbiol Spectr. 2023 Jun 15;11 (3) :e0308022.|Al-Rafidain Journal of Medical Sciences. 2025 Feb 11.|bioRxiv. 2020 Apr.|Cell Rep. 2025 Jul 22;44 (7) :115987. |Front Cell Infect Microbiol. 2021 Mar 25;11:660431.|Front Microbiol. 2024 Sep 24:15:1417237.|J Antimicrob Chemother. 2021 Dec 24;77 (1) :58-68.|Microb Drug Resist. 2020 Jun;26 (6) :550-560.|Microb Pathog. 2023 Dec:185:106397.|Microbiol Spectr. 2025 Sep 2;13 (9) :e0114425.|mSphere. 2023 Apr 20;8 (2) :e0067322.|World J Microbiol Biotechnol. 2024 Jun 6;40 (8) :233.

• CAS Number:

  [115871-02-8]