LY-2434074

• Description:

  LY-2434074 is a selective β-secretase (BACE) inhibitor with an IC50 amyloid-β (Aβ40 and Aβ42) production. LY-2434074 can be used for the research of neurological disease, such as Alzheimer's disease[1].

• UNSPSC:

  12352005

• Target:

  Amyloid-β; Beta-secretase

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  O[C@H]([C@]1([H])N[C@H]([C@@H](OC1)OCC(C)(C)C)C)[C@@H](NC(C)=O)CC2=CC(F)=CC(F)=C2.Cl

• Molecular Formula:

  C21H33ClF2N2O4

• Molecular Weight:

  450.95

• References & Citations:

  [1]Timothy Barrett Durham, et al. 3- (2-acylamino-1-hydroxyethyl) - morpholine derivatives and their use as bace inhibitors. WO2006034093A2. 2006-03-30

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [883446-27-3]