JTE-013 (Standard)

CAT: 0804-HY-100675R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100675R-01Size:5 mg
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Description
JTE-013 (Standard) is the analytical standard of JTE-013. This product is intended for research and analytical applications. JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively[1].
CAS Number
[383150-41-2]
UNSPSC
12352005
Target
Apoptosis; LPL Receptor; Reference Standards
Related Pathways
Apoptosis; GPCR/G Protein; Others
Field of Research
Cancer
Smiles
CC(C1=C2C(N(C)N=C2C)=NC(NNC(NC3=CC(Cl)=NC(Cl)=C3)=O)=C1)C
Molecular Formula
C17H19Cl2N7O
Molecular Weight
408.29
References & Citations
[1]Li MH, et al. Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma. J Pharmacol Exp Ther. 2015 Sep;354 (3) :261-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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