JTE-013 (Standard)

• Description:

  JTE-013 (Standard) is the analytical standard of JTE-013. This product is intended for research and analytical applications. JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; LPL Receptor; Reference Standards

• Related Pathways:

  Apoptosis; GPCR/G Protein; Others

• Field of Research:

  Cancer

• Smiles:

  CC(C1=C2C(N(C)N=C2C)=NC(NNC(NC3=CC(Cl)=NC(Cl)=C3)=O)=C1)C

• Molecular Formula:

  C17H19Cl2N7O

• Molecular Weight:

  408.29

• References & Citations:

  [1]Li MH, et al. Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma. J Pharmacol Exp Ther. 2015 Sep;354 (3) :261-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [383150-41-2]