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Caryophyllene oxide

CAT: 0804-HY-N3544-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3544-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Caryophyllene oxide ((-) -Caryophyllene oxide) is a bicyclic sesquiterpene with anticancer effects. Caryophyllene oxide induces apoptosis of PC-3 cells. Caryophyllene oxide shows analgesic and anti-inflammatory activities. Caryophyllene oxide has insecticidal, antioxidant, antimicrobial, antifungal, and antiparasitic properties[1][2][3].
CAS Number
1139-30-6
Product Name Alternative
(-) -Caryophyllene oxide
UNSPSC
12352005
Hazard Statement
H315, H319, H411
Target
Apoptosis; Bacterial; Fungal; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/caryophyllene-oxide.html
Concentration
10mM
Purity
99.71
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
C=C1CC[C@@]2([H])O[C@]2(C)CC[C@@]3([H])C(C)(C)C[C@]13[H]
Molecular Formula
C15H24O
Molecular Weight
220.35
Precautions
H315, H319, H411
References & Citations
[1]Chavan MJ, et al. Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark. Phytomedicine. 2010 Feb;17 (2) :149-51.|[2]Delgado C, et al. Caryophyllene Oxide, the Active Compound Isolated from Leaves of Hymenaea courbaril L. (Fabaceae) with Antiproliferative and Apoptotic Effects on PC-3 Androgen-Independent Prostate Cancer Cell Line. Molecules. 2021 Oct 12;26 (20) :6142. |[3]Coté H, et al. Anti-Inflammatory, Antioxidant, Antibiotic, and Cytotoxic Activities of Tanacetum vulgare L. Essential Oil and Its Constituents. Medicines (Basel) . 2017 May 25;4 (2) :34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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1139-30-6Caryophyllene Oxide
sc-257221(-) -Caryophyllene oxide
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