β-Caryophyllene

• UNSPSC Description:

  β-Caryophyllene is a CB2 receptor agonist.

• Target Antigen:

  Cannabinoid Receptor; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/_beta_-Caryophyllene.html

• Purity:

  99.55

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)|Ethanol : ≥ 176.67 mg/mL|H2O : < 0.1 mg/mL

• Smiles:

  C=C1CC/C=C(C)/CC[C@@]2([H])C(C)(C)C[C@]12[H]

• Molecular Weight:

  204.35

• References & Citations:

  [1]Cheng Y, et al. β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway. Pharmacology. 2014;94(1-2):1-12.|[2]Dahham SS, et al. The Anticancer, Antioxidant and Antimicrobial Properties of the Sesquiterpene β-Caryophyllenefrom the Essential Oil of Aquilaria crassna. Molecules. 2015 Jun 26;20(7):11808-29.|[3]de Oliveira CC, et al. Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures. Epilepsy Behav. 2016 Mar;56:26-31.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Phase 3

• CAS Number:

  87-44-5