(R) -MK-8353

• Target:

  ERK

• Related Pathways:

  MAPK

• Bioactivity:

  (R) -MK-8353 ((R) -SCH900353) is the R-enantiomer of MK-8353. MK-8353 (SCH900353) is a potent, selective, orally active inhibitor of ERK1 and ERK2, with IC50 values of 23.0 nM and 8.8 nM, respectively.

• Smiles:

  N (C (=O) [C@]1 (SC) CN (CC (=O) N2CCC (=CC2) C3=CC=C (C=C3) C4=NN (C) C=N4) CC1) C=5C=C6C (=NNC6=CC5) C=7C=CC (OC (C) C) =NC7

• Molecular Formula:

  C37H41N9O3S

• Molecular Weight:

  691.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2748457-30-7