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TAT-EE3

CAT: 0931-TP3908-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3908-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2899218-49-4
Target
Calcium Channel, iGluR, TRP/TRPV Channel
Related Pathways
Neuroscience, Metabolism, Membrane transporter/Ion channel
Bioactivity
TAT-EE3 is a neuroprotective peptide that dissociates the interaction between TRPM2 and NMDARs. It inhibits the TRPM2-induced enhancement of NMDAR surface expression and current amplitude. TAT-EE3 protects neurons from ischemic damage both in vitro and in vivo, and is utilized for research on ischemic stroke.
Smiles
[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CCC(O)=O)=O)C)=O)CC(C)C)=O)C)=O)CC(C)C)=O)CCSC)=O)CCC(O)=O)=O)CCC(O)=O)=O)CO)=O)CO)=O)CC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=C(O)C=C1)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N
Molecular Formula
C135H228N48O49S
Molecular Weight
3339.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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