TAT-EE3

CAT: 0804-HY-P11117-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P11117-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TAT-EE3 is a neuroprotective peptide which can uncouple TRPM2-NMDARs interaction. TAT-EE3 inhibits TRPM2-induced enhancement of NMDAR surface expression and current amplitude.TAT-EE3 protects neurons against ischemic injury in vitro and in vivo. TAT-EE3can be used for the study of ischemic stroke[1].
CAS Number
[2899218-49-4]
UNSPSC
12352209
Target
Calcium Channel; iGluR; TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Purity
99.89
Solubility
H2O : 5.88 mg/mL (ultrasonic; adjust pH to 9 with NH3·H2O)
Smiles
O=C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC1=CC=C(C=C1)O)N
Molecular Formula
C135H228N48O49S
Molecular Weight
3339.61
References & Citations
[1]Zong P, et al. Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury. Neuron. 2022 Jun 15;110 (12) :1944-1958.e8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P0281-01TAT
HY-P5883-01TAT-M2NX
HY-P0282TAT peptide
HY-P5281TAT-GluN2B
HY-P2193-01TAT-amide
HY-P10995TAT-327
HY-P10438-01TAT-Braftide
HY-P10638-01TAT-CN21
HY-P10465TRPV1-Tat
HY-P10357TAT-CBD3

Alternative Products

CatalogName
MF-0127439-01TAT-EE3
068-27TAT Derivative, R9-Tat
abx600187-01Protein Tat (TAT) Protein
M30507-01TAT
E8ER1919-19α-TAT
CRB1001142-01TAT - GluR23Y - (TAT Conjugated Peptides)
CRB1001584-01TAT-CN21 - (TAT Conjugated Peptides)
C13526-01Tat-beclin 1 (Tat-BECN1)
MBS9379211Plant Tat Protein (TAT) ELISA Kit
CRB1000911-01TAT-Beclin Scrambled - (TAT Conjugated Peptides)

Popular Products