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TAT-CBD3A6K

CAT: 0931-TP3542-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3542-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1505463-57-9
Target
Calcium Channel
Related Pathways
Metabolism, Membrane transporter/Ion channel
Bioactivity
TAT-CBD3A6K is a modified TAT-CBD3 peptide. It reduces T-type and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. By inhibiting CRMP-2-mediated enhancement of T-type and R-type calcium channel function, TAT-CBD3A6K exhibits anti-nociceptive effects in models of AIDS-induced peripheral neuropathy.
Smiles
C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)CCCNC(=N)N)(=O)[C@H]1N(C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C)=O)CCCNC(=N)N)=O)CO)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)CCC1
Molecular Formula
C137H250N60O32
Molecular Weight
3249.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C